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Department of Pharmaceutical Chemistry

Department of Pharmaceutical Chemistry

The educational and scientific studies in the Department of Pharmaceutical Chemistry has been begun in 2002. Until today, 16 students have graduated from the Master's (with Thesis) Program in the Department of Pharmaceutical Chemistry and 1 student from the doctoral program. Currently, 4 master's and 3 doctoral students continue their education in the Department.

The academic staffs in the department continue to their original researches about various heterocyclic compounds, platinum complexes and primarily anticancer and other pharmacological activities and the publication of the research results in national/international journals/books and educational activities since 2002. The research activities and projects of the department are support by several institutions including Mersin University, TUBITAK, and other institutions and organizations.

There are several equipments in our research laboratories such as a microwave synthesis system, IR Spectroscopy, flahs chromotography system, melting point system, the route evaporators, vacuum pump, oven / vacuum oven and scales using during the studies, cooler and magnetic stirrer heating.

The studies and researches of the department are carried out in two laboratories of the faculty and new research laboratories established in Mersin University Advanced Technology, Training, Research and Application Center (MEİTAM).

The academic staffs serve on various committees, boards and departments in the university. The academic staff also participate as editor or reviewer in various national and international journals as well as panelist, reviewer, or adviser in the research projects supported by TUBITAK.





Publications in International Scientific Journals(last two years)

19. Kuzu, B.; Sari, O.; Erdem, S.; Algul, O.; Menges, N. Synthesis of Benzoxazole‐2‐carboxylate Derivatives: Electronic‐ and Position‐effect of Functional Groups and Computational Modeling of the Selectivity for Oxazole Ring. CHEMISTRYSELECT, 2021, 6, 2529-2538.
18. Ersan, R.; Yuksel, A.; Ertan‐bolelli, T.; Dogen, A.; Burmaoglu, S.; Algul, O. One‐pot synthesis of novel benzimidazoles with a naphthalene moiety as antimicrobial agents and molecular docking studies. WILEY, 2020, 1-10.
17. Ersan, R.; Alagoz, M.; Ertan-bolelli, T.; Duran, N.; Burmaoglu, S.; Algul, O. Head-to-head bisbenzazole derivatives as antiproliferative agents: design, synthesis, in vitro activity, and SAR analysis. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2020, 2020, 1-10.
16. Algul, O.; Ersan, R.; Alagoz, M.; Duran, N.; Burmaoglu, S. An efficient synthesis of novel di-heterocyclic benzazole derivatives and evaluation of their antiproliferative activities. INFORMA UK LIMITED, 2020, 2020, 1-13.
15. Duran, G.; Küçük, M.; Algül, .; Terzi, M. Investigation of New Benzimidazole Derivative Compounds’ Effects on A549 Cell Line. FAPUNIFESP (SCIELO), 2020, 63, 1-8.
14. özdemir, Z.; Utku, S.; Mathew, .; Carradori, S.; Orlando, G.; Di simone, S.; Alagoz, M.; Ozcelik, A.; Uysal, M. Synthesis and biological evaluation of new 3(2H)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , 2020, 35, 1100-1109.
13. Aktaş, D.; Akinalp, G.; Sanli, F.; Yucel, M.; Gambacorta, N.; Nicolotti, O.; Karatas, O.; Algul, O.; Burmaoglu, S. Design, synthesis and biological evaluation of 3,5-diaryl isoxazole derivatives as potential anticancer agents. ELSEVIER BV, 2020, 30, 127427-127427.
12. Aktas, D.; Akınalp, G.; Sanlıalp, F.; Yücel, M.; Gambacortae, N.; Nicolottie, O.; Karatasc, O.; Algül, .; Burmaoğlu, S. . BIOORGANIC MEDICINAL CHEMISTRY LETTERS, 2020, 30, 127427-.
11. Burmaoğlu, S.; Kazancıoğlu, E.; Kaya, R.; Kazancıoğlu, M.; Karaman, M.; Algül, .; Gülçin, . . JOURNAL OF MOLECULAR STRUCTURE, 2020, 1208, 127868-127868.
10. Ayaz, F.; Ersan, R.; Kuzu, B.; Algul, O. New-Generation Benzimidazole-Based Plasmid Delivery Reagents with High Transfection Efficiencies on the Mammalian Cells. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2020, 56, 34-41.
9. Ersan, R.; Yuksel, A.; Ertan‐bolelli, T.; Dogen, A.; Burmaoglu, S.; Algul, O. One‐pot synthesis of novel benzimidazoles with a naphthalene moiety as antimicrobial agents and molecular docking studies. J CHIN CHEM SOC., 2020, 68, 374-383.
8. Ersan, R.; Alagöz, M.; Ertan bolelli, T.; Duran, N.; Burmaoğlu, S.; Algül, . . MOLECULAR DIVERSITY, 2020, , -.
7. Ayaz, F.; Ronak haj, E.; Algül, . . MONATSHEFTE FUR CHEMIE - CHEMICAL MONTHLY, 2019, 150, 1137-1146.
6. özçelik, A.; özdemir, Z.; Sari, S.; Utku, S.; Uysal, M. A new series of pyridazinone derivatives as cholinesterases inhibitors: Synthesis, in vitro activity and molecular modeling studies. PHARMACOLOGICAL REPORTS, 2019, 71, 1253-1263.
5. Gülçin, .; Kaya, R.; Algül, .; Yilmaz, A.; Burmaoglu, S. . BIOORGANIC CHEMISTRY, 2019, 85, 191-197.
4. Kuzu, B.; Ayaz, F.; Algül, . . JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56, 1946-1952.
3. Ayaz, F.; Rusmeenee, K.; Qadar ahmed, I.; Ronak haj, E.; Algül, . . TURKISH JOURNAL OF CHEMISTRY, 2019, 43, 963-971.
2. Burmaoğlu, S.; özcan, .; Balcıoğlu, S.; Gencel, M.; Noma, S.; Eşsiz gökhan, .; Ateş, B.; Algül, . . BIOORGANIC CHEMISTRY, 2019, 91, -.
1. Burmaoğlu, S.; Yılmaz, A.; Polat, M.; Kaya, R.; Gülçin, .; Algül, . . ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2019, , -.