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Department of Basic Pharmaceutical Sciences

Department of Basic Pharmaceutical Sciences

Department of Basic Pharmaceutical Sciences consists of three main branches of science, as indicated below:

 

Department of Analytical Chemistry,

Department of Biochemistry,

Department of Pharmaceutical Microbiology

 


Publications in International Scientific Journals(last two years)

2021
40. Nural, Y.; Keleş, E.; Aydıner, B.; Seferoglu, N.; Atabey, H.; Seferoglu, Z. New naphthoquinone-imidazole hybrids: Synthesis, anion recognition properties, DFT studies and acid dissociation constants. JOURNAL OF MOLECULAR LIQUIDS, 2021, 327, 114855-114855.
http://www.sciencedirect.com/science/article/pii/S0167732220370975
39. Efsun antmen, S.; Canacankatan, N.; Gürses, .; Aytan, H.; Erden ertürk, S. Relevance of lipogenesis and AMPK/Akt/mTOR signaling pathway in endometrial cancer. EUR REV MED PHARMACOL SCI , 2021, 25, 687-695.
https://doi.org/10.26355/eurrev_202101_24630
2020
38. Vural, E.; Delialioğlu, N.; Tezcan ulger, S.; Emekdas, G.; Serin, M. Phenotypic and Molecular Detection of the Metallo-Beta-Lactamases in Carbapenem-Resistant Pseudomonas aeruginosa Isolates from Clinical Samples. KOWSAR MEDICAL INSTITUTE, 2020, 13, 0-0.
http://dx.doi.org/10.5812/jjm.90034
37. öksüz, Z.; üçbilek, E.; Serin, M.; Yaraş, S.; Temel, G.; Sezgin, O. Circulating vascular adhesion protein-1(VAP-1): a possible biomarker for liver fibrosis associated with chronic hepatitis B and C. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2020, 3, 1-10.
http://dx.doi.org/10.1007/s42770-020-00379-x
36. Ağırtaş, M.; Cabir, B.; Yıldıko, .; özdemir, S.; Gonca, S. Synthesis, antioxidant, DNA cleavage and antimicrobial properties of phthalocyanine complexes bearing the poly-hydroxyl groups. CHEMICAL PAPERS, 2020, 1, 1-12.
http://dx.doi.org/10.1007/s11696-020-01432-7
35. Uckun, Z.; Guzel, S.; Canacankatan, N.; Yalaza, C.; Kibar, D.; Coskun yilmaz, B. Potential protective effects of naringenin against vancomycin-induced nephrotoxicity via reduction on apoptotic and oxidative stress markers in rats. DRUG CHEM TOXICOL., 2020, 43, 104-111.
http://dx.doi.org/10.1080/01480545.2018.1512612
34. Nural, Y.; Ozdemir, S.; Doluca, O.; Demir, B.; Yalcin, M.; Atabey, H.; Kanat, B.; Erat, S.; Sari, H. Synthesis, biological properties, and acid dissociation constant of novel naphthoquinone–triazole hybrids.. BIOORGANIC CHEMISTRY, 2020, 105, 104441-104441.
https://www.sciencedirect.com/science/article/abs/pii/S0045206820317399
33. Arpaci, A.; Yalın, S.; Ecevit, H.; Comelekoglu, U.; Mete, T. Enzyme activity and genetic polymorphisms in patients with type II diabetes mellitus. WROCLAW MEDICAL UNIVERSITY, 2020, 29, 1057-1063.
http://dx.doi.org/10.17219/acem/125397
32. Belveren, S.; Poyraz, S.; ülger, M.; Pask, C.; Döndaş, H.; Sansano, J. Synthesis, structure and bioactivity of a mononuclear octahedral [Prolinate2-Na(MeOH)4]−H+ complex. INORGANICA CHIMICA ACTA, 2020, 504, 119456-119456.
Publications_044.pdf
31. Yalaza, C.; Canacankatan, N.; Gürses, .; Aytan, H.; Taşdelen, B. Altered VEGF, Bcl-2 and IDH1 expression in patients with adenomyosis. ARCH GYNECOL OBSTET., 2020, 302, 1221-1227.
http://dx.doi.org/10.1007/s00404-020-05742-9
30. Kirik, F.; ülger, M.; Tezcan ülger, S.; Aslan, G. Association of cytokine gene polymorphisms with susceptibility to cutaneous leishmaniasis in a Turkish population. PARASITE IMMUNOL, 2020, 13, 12775-12775.
Publications_046.pdf
29. ınce, T.; Serttas, R.; Demir, B.; Atabey, H.; Seferoglu, N.; Erdogan, S.; Sahin, E.; Erat, S.; Nural, Y. Polysubstituted pyrrolidines linked to 1,2,3-triazoles: Synthesis, crystal structure, DFT studies, acid dissociation constant, drug-likeness, and anti-proliferative activity. JOURNAL OF MOLECULAR STRUCTURE, 2020, 1217, 128400-128400.
http://dx.doi.org/10.1016/j.molstruc.2020.128400
28. öksüz, Z.; üçbilek, E.; Serin, M.; Yaraş, S.; Temel, G.; Sezgin, O. Circulating vascular adhesion protein-1(VAP-1): a possible biomarker for liver fibrosis associated with chronic hepatitis B and C. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2020, 51, 1757-1763.
http://dx.doi.org/10.1007/s42770-020-00379-x
27. Berköz, M.; Yıldırım, M.; Yalın, S.; Ilhan, M.; Yunusoğlu, O. Myricetin inhibits angiotensin converting enzyme and induces nitric oxide production in HUVEC cell line. AEPRESS, S.R.O., 2020, 39, 249-258.
http://dx.doi.org/10.4149/gpb_2020007
26. Keleş, E.; Aydıner, B.; Nural, Y.; Seferoğlu, N.; şahin, E.; Seferoğlu, Z. A mechanism for selective recognition of cyanide in organic and aqueous solution. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2020, 2020, 4681-4692.
10.1002/ejoc.202000342
25. Erşatır, M.; Yıldırım, M.; Giray, E.; Yalın, S. Synthesis and antiproliferative evaluation of novel biheterocycles based on coumarin and 2-aminoselenophene-3-carbonitrile unit. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2020, 151, 625-636.
http://dx.doi.org/10.1007/s00706-020-02573-x
24. Guzel, S.; Sahinogullari, Z.; Canacankatan, N.; Antmen, S.; Kibar, D.; Coskun yilmaz, B. Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity in rats. DRUG CHEM TOXICOL, 2020, 43, 630-636.
http://dx.doi.org/10.1080/01480545.2019.1584208
23. Barlaz us, S.; Vezir, O.; Yildirim, M.; Bayrak, G.; Yalin, S.; Balli, E.; Yalin, A.; çömelekoğlu, . Protective effect of N-acetyl cysteine against radiotherapy-induced cardiac damage. INFORMA UK LIMITED, 2020, 96, 661-670.
http://dx.doi.org/10.1080/09553002.2020.1721605
22. Güzel, S.; ülger, M.; Kahraman, A. Chemical Composition and Some Biological Activities of Salvia longipedicellata Hedge Mericarps. CHEMISTRY OF NATURAL COMPOUNDS, 2020, 56, 788-792.
Publications_047.pdf
2019
21. Kaplan, E.; Gonca, S.; Kandemir, H.; Döğen, A.; Hilmioğlu-polat, S.; ılkit, M.; Tanaka, R.; Yaguchi, T.; Uhrlaβ, S. Genes Encoding Proteolytic Enzymes Fungalysin and Subtilisin in Dermatophytes of Human and Animal Origin: A Comparative Study. MYCOPATHOLOGIA, 2019, 184, 0-0.
http://dx.doi.org/10.1007/s11046-019-00367-2
20. Ergin, .; şengül, M.; Aksoy, L.; Döğen, A.; Sun, S.; Averette, A.; Cuomo, C.; Seyedmousavi, S.; Heitman, J. Cryptococcus neoformans Recovered From Olive Trees (Olea europaea) in Turkey Reveal Allopatry With African and South American Lineages. FRONTIERS MEDIA SA, 2019, 9, 1-10.
http://dx.doi.org/10.3389/fcimb.2019.00384
19. Binzet, R.; Binzet, G.; Gumus, I.; Turunc, E.; Solmaz, U.; Keskin, E.; Dogen, A.; Arslan, H. Chemical Composition and Antimicrobial Activity of Essential Oil and Various Extracts of Onosma sieheana Hayek Roots. INFORMA UK LIMITED, 2019, 1, 1-11.
http://dx.doi.org/10.1080/0972060X.2019.1600431
18. Kaplan, E.; Gonca, S.; Kandemir, H.; Döğen, A.; Hilmioğlu-polat, S.; ılkit, M.; Tanaka, R.; Yaguchi, T.; Uhrlaβ, S. Genes Encoding Proteolytic Enzymes Fungalysin and Subtilisin in Dermatophytes of Human and Animal Origin: A Comparative Study. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2019, 1-12.
http://dx.doi.org/10.1007/s11046-019-00367-2
17. Kaplan, E.; Aktaş, D.; önder, .; Metin, B.; Döğen, A.; Oz, Y.; ılkit, M. Mating genotypes and susceptibility profiles of clinical isolates of Candida glabrata from Turkey. WILEY, 2019, 1, 1-5.
http://dx.doi.org/10.1111/myc.12945
16. Eras, N.; Türkoz, G.; Tombak, A.; Tiftik, E.; Yalın, S.; Berkoz, M.; Erden, S.; Akbaş, E. . ARCHIVES OF MEDICAL SCIENCE, 2019, , 1-6.
89692
15. Belveren, S.; Poyraz, S.; Pask, C.; ülger, M.; Sansano, J.; Ali döndaş, H. Synthesis and biological evaluation of platinum complexes of highly functionalized aroylaminocarbo-N-thioyl prolinate containing tetrahydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione moieties. INORGANICA CHIMICA ACTA, 2019, 498, 119154-119154.
http://dx.doi.org/10.1016/j.ica.2019.119154
14. Guzel, S.; Ozay, Y.; Kumas, M.; Uzun, C.; Ozkorkmaz, E.; Yildirim, Z.; Ulger, M.; Guler, G.; Celik, A. Wound healing properties, antimicrobial and antioxidant activities of Salvia kronenburgii Rech. f. and Salvia euphratica Montbret, Aucher & Rech. f. var. euphratica on excision and incision wound models in diabetic rats. BIOMEDICINE & PHARMACOTHERAPY, 2019, 111, 1260-1276.
https://dx.doi.org/10.1016/j.biopha.2019.01.038
13. öksüz, Z.; Serin, M.; Serin, A.; Sezgin, O.; Gonca, S. Determination of Reverse Transcriptase Inhibitor Nucleoside Analogue Resistance Profile in Pretreatment Phase of Patients with Viral Hepatitis B. MIKROBIYOLOJI BULTENI, 2019, 53, 156-169.
Publications_018.pdf
12. Belveren, S.; Dondas, H.; Sansano, J.; Larrañaga, O.; Poyraz, S.; ülger, M.; şahin, E.; Ferrándiz-saperas, M.; De gracia retamosa, M. From Bioactive Pyrrolidino[3,4-c]pyrrolidines to more Bioactive Pyrrolidino[3,4-b]pyrrolidines via Ring-Opening/Ring-Closing Promoted by Sodium Methoxide. GEORG THIEME VERLAG KG, 2019, 51, 1565-1577.
http://dx.doi.org/10.1055/s-0037-1611356
11. Belveren, S.; Larrañaga, O.; Poyraz, S.; Döndaş, H.; ülger, M.; şahin, E.; Ferrándiz-saperas, M.; Sansano, J.; Gracia retamosa, D. From Bioactive Pyrrolidino[3,4-c]pyrrolidines to more Bioactive Pyrrolidino[3,4-b]pyrrolidines via Ring-Opening/Ring-Closing Promoted by Sodium Methoxide. SYNTHESIS, 2019, 51, 1595-1577.
10.1055/s-0037-1611356
10. Ergin, .; şengül, M.; Döğen, A.; Ilkit, M. Prediction of the Species Distribution of Cryptococcus neoformans Throughout Turkey . MIKROBIYOLOJI BULTENI, 2019, 53, 233-238.
10.5578/mb.67999
9. Metin, B.; Döğen, A.; Yıldırım, E.; De hoog, G.; Heitman, J.; ılkit, M. Mating type (MAT) locus and possible sexuality of the opportunistic pathogen Exophiala dermatitidis. ELSEVIER BV, 2019, 124, 29-38.
http://dx.doi.org/10.1016/j.fgb.2018.12.011
8. Tezcan ülger, S.; Kurnaz, N.; ülger, M.; Aslan, G.; Emekdaş, G. Serological Evidence of Rift Valley Fever Virus Among Humans in Mersin Province of Turkey. J VECTOR BORNE DIS, 2019, 56, 373-379.
Publications_042.pdf
7. Berköz, M.; özkan yılmaz, F.; özlüer hunt, A.; Gündüz, S.; Yıldırım, M.; Yalın, S. . FRESENIUS ENVIRONMENTAL BULLETIN, 2019, 28, 4642-4649.
6. öksüz, Z.; Serin, M.; Serin, A.; Sezgin, O.; Gonca, S. Düzeltme/Erratum. MIKROBIYOLOJI BULTEMIKROBIYOL BULNI, 2019, 53, 480-480.
Publications_017.pdf
5. Barlaz us, S.; Söğüt, F.; Yıldırım, M.; Yetkin, D.; Yalın, S.; Yılmaz, .; çömelekoğlu, . . CANCER INVESTIGATION, 2019, 37, 489-500.
10.1080/07357907.2019.1662434
4. Gemili, M.; Nural, Y.; Keleş, E.; Aydıner, B.; Seferoğlu, N.; ülger, M.; şahin, E.; Erat, S.; Seferoğlu, Z. Novel highly functionalized 1,4-naphthoquinone 2-iminothiazole hybrids: Synthesis, photophysical properties, crystal structure, DFT studies, and anti(myco)bacterial/antifungal activity. JOURNAL OF MOLECULAR STRUCTURE, 2019, 1196, 536-546.
http://dx.doi.org/10.1016/j.molstruc.2019.06.087
3. şengül, M.; Kutlu, M.; Döğen, A.; Aksoy, L.; Gonca, S.; Ilkit, M.; Ergin, . Isolation of Cryptococcus neoformans from a Chesnut Tree (Castanea sativa), Denizli, Turkey . MIKROBIYOLOJI BULTENI, 2019, 53, 61-69.
10.5578/mb.67583
2. şengül, M.; Kutlu, M.; Döğen, A.; Aksoy, L.; Gonca, S.; Ilkit, M.; Ergin, . Isolation of Cryptococcus neoformans from a Chesnut Tree (Castanea sativa), Denizli, Turkey. MIKROBIYOLOJI BULTENI, 2019, 53 , 61-69.
Publications_005.pdf
1. çelik, A.; Güler, G.; Aktaş, C.; Yalın, S. . BIOMARKERS, 2019, 24, 720-725.
10.1080/1354750X.2019.1658804