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Department of Basic Pharmaceutical Sciences

Department of Basic Pharmaceutical Sciences

Department of Basic Pharmaceutical Sciences consists of three main branches of science, as indicated below:

 

Department of Analytical Chemistry,

Department of Biochemistry,

Department of Pharmaceutical Microbiology

 


Son İki Yılda Uluslararası Dergilerde Yayınlanan Makaleler

2019
35. Binzet, R.; Binzet, G.; Gumus, I.; Turunc, E.; Solmaz, U.; Keskin, E.; Dogen, A.; Arslan, H. Chemical Composition and Antimicrobial Activity of Essential Oil and Various Extracts of Onosma sieheana Hayek Roots. INFORMA UK LIMITED, 2019, 1, 1-11.
http://dx.doi.org/10.1080/0972060X.2019.1600431
34. Kaplan, E.; Aktaş, D.; önder, .; Metin, B.; Döğen, A.; Oz, Y.; ılkit, M. Mating genotypes and susceptibility profiles of clinical isolates of Candida glabrata from Turkey. WILEY, 2019, 1, 1-5.
http://dx.doi.org/10.1111/myc.12945
33. Güzel, S.; şahinoğulları, Z.; canacankatan, N.; Antmen, E.; Kibar, D.; Yılmaz, B. “Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity in rats. DRUG CHEM TOXICOL, 2019, 12, 1-7.
32. öksüz, Z.; Serin, M.; Serin, A.; Sezgin, O.; Gonca, S. Determination of Reverse Transcriptase Inhibitor Nucleoside Analogue Resistance Profile in Pretreatment Phase of Patients with Viral Hepatitis B. MIKROBIYOLOJI BULTENI, 2019, 53, 156-169.
http://www.mikrobiyolbul.org/journal_issue.aspx?issue_id=212
31. Dondas, H.; Sansano, J.; Belveren, S.; Larrañaga, O.; Poyraz, S.; ülger, M.; şahin, E.; Ferrándiz-saperas, M.; De gracia retamosa, M. From Bioactive Pyrrolidino[3,4-c]pyrrolidines to more Bioactive Pyrrolidino[3,4-b]pyrrolidines via Ring-Opening/Ring-Closing Promoted by Sodium Methoxide. SYNTHESIS, 2019, 51, 1565-1577.
http://dx.doi.org/10.1055/s-0037-1611356
30. Ergin, .; şengül, M.; Döğen, A.; Ilkit, M. Prediction of the Species Distribution of Cryptococcus neoformans Throughout Turkey . MIKROBIYOLOJI BULTENI, 2019, 53, 233-238.
10.5578/mb.67999
29. Metin, B.; Döğen, A.; Yıldırım, E.; De hoog, G.; Heitman, J.; ılkit, M. Mating type (MAT) locus and possible sexuality of the opportunistic pathogen Exophiala dermatitidis. ELSEVIER BV, 2019, 124, 29-38.
http://dx.doi.org/10.1016/j.fgb.2018.12.011
28. Gemili, M.; Nural, Y.; Keleş, E.; Aydıner, B.; Seferoğlu, N.; ülger, M.; şahin, E.; Erat, S.; Seferoğlu, Z. Novel highly functionalized 1,4-naphthoquinone 2-iminothiazole hybrids: Synthesis, photophysical properties, crystal structure, DFT studies, and anti(myco)bacterial/antifungal activity. JOURNAL OF MOLECULAR STRUCTURE, 2019, 1196, 536-546.
http://dx.doi.org/10.1016/j.molstruc.2019.06.087
27. şengül, M.; Kutlu, M.; Döğen, A.; Aksoy, L.; Gonca, S.; Ilkit, M.; Ergin, . Isolation of Cryptococcus neoformans from a Chesnut Tree (Castanea sativa), Denizli, Turkey . MIKROBIYOLOJI BULTENI, 2019, 53, 61-69.
10.5578/mb.67583
2018
26. Belveren, S.; Larrañaga, O.; Poyraz, S.; Döndaş, H.; ülger, M.; şahin, E.; Ferrándiz-saperas, M.; Sansano, J.; De gracia retamosa, M. From Bioactive Pyrrolidino[3,4-c]pyrrolidines to more Bioactive Pyrrolidino[3,4-b]pyrrolidines via Ring-Opening/Ring-Closing Promoted by Sodium Methoxide. GEORG THIEME VERLAG KG-SYNTHESIS , 2018, 0-0.
http://dx.doi.org/10.1055/s-0037-1611356
25. Belveren, S.; Larrañaga, O.; Poyraz, S.; Döndaş, H.; ülger, M.; şahin, E.; Ferrándiz-saperas, M.; Sansano, J.; De gracia retamosa, M. From Bioactive Pyrrolidino[3,4-c]pyrrolidines to more Bioactive Pyrrolidino[3,4-b]pyrrolidines via Ring-Opening/Ring-Closing Promoted by Sodium Methoxide. SYNTHESIS -GEORG THIEME VERLAG KG, 2018, 50, 0-0.
http://dx.doi.org/10.1055/s-0037-1611356
24. Uçkun, Z.; Guzel, S.; Canacankatan, N.; Yalaza, C.; Kibar, D.; Yılmaz, B. Potential protective effects of naringenin against vancomycin-induced nephrotoxicity via reduction on apoptotic and oxidative stress markers in rats. DRUG AND CHEMICAL TOXICOLOGY , 2018, 27, 1-8.
10.1080/01480545.2018.1512612.
23. eti, C.; Vayısoğlu, .; Kardaş, B.; Bozdogan arpacı, R.; sahin horasan, E.; kanık, A.; eti, N.; Yalın, S.; ümit talas, D. Histopathologic evaluation of Ecballium elaterium applied to nasal mucosa in a rat rhinosinusitis model . EAR NOSE THROAT J. , 2018, 97, 14-17.
22. çalhan, S.; Alaş, M.; Aşık, M.; Kaya, F.; Genç, R. One-pot synthesis of hydrophilic and hydrophobic fluorescent carbon dots using deep eutectic solvents as designer reaction media. SPRINGER NATURE AMERICA, INC, 2018, 53, 15362-15375.
http://dx.doi.org/10.1007/s10853-018-2723-4
21. Döğen, A. . GENETICS, 2018, 208, 1657-1669.
10.1534/genetics.117.300573
20. Nural, Y. Synthesis, antimycobacterial activity, and acid dissociation constants of polyfunctionalized 3-[2-(pyrrolidin-1-yl)thiazole-5-carbonyl]-2H-chromen-2-one derivatives. MONATSHEFTE FUR CHEMIE - CHEMICAL MONTHLY, 2018, 149, 1905-1918.
http://dx.doi.org/10.1007/s00706-018-2250-7
19. Solmaz, U.; Gumus, I.; Binzet, G.; Celik, O.; Balci, G.; Dogen, A.; Arslan, H. Synthesis, characterization, crystal structure, and antimicrobial studies of novel thiourea derivative ligands and their platinum complexes. INFORMA UK LIMITED, 2018, 71, 200-218.
http://dx.doi.org/10.1080/00958972.2018.1427233
18. Poyraz, S.; Canacankatan, N.; Belveren, S.; Yetkin, D.; Kibar, K.; ülger, M.; Sansano, J.; özcelik, N.; Necat yılmaz, . Study of the anti(myco)bacterial and antitumor activities of prolinate and N-amidocarbothiolprolinate derivatives based on fused tetrahydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione, bearing an indole ring. SPRINGER NATURE AMERICA, INC-MONATSHEFTE FUR CHEMIE, 2018, 149, 2253-2263.
http://dx.doi.org/10.1007/s00706-018-2286-8
17. Poyraz, S.; Canacankatan, N.; Belveren, S.; Yetkin, D.; Kibar, K.; ülger, M.; Sansano, J.; özcelik, N.; Necat yılmaz, . Study of the anti(myco)bacterial and antitumor activities of prolinate and N-amidocarbothiolprolinate derivatives based on fused tetrahydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione, bearing an indole ring. MONATSHEFTE FUR CHEMIE - CHEMICAL MONTHLY, 2018, 149-, 2253-2263.
http://dx.doi.org/10.1007/s00706-018-2286-8
16. Dündar, Y.; ülger, M.; Kaynak onurdağ, F.; ökten, S.; önkol, T. . REV. ROUM. CHIM., 2018, 63, 265-272.
15. Boral, H.; Metin, B.; Döğen, A.; Seyedmousavi, S.; ılkit, M. Overview of selected virulence attributes in Aspergillus fumigatus , Candida albicans , Cryptococcus neoformans , Trichophyton rubrum , and Exophiala dermatitidis. ELSEVIER BV, 2018, 17, 30153-301536.
http://dx.doi.org/10.1016/j.fgb.2017.10.008
14. Millington, E.; Dondas, H.; Fishwick, C.; Kilner, C.; Grigg, R. Catalytic bimetalic [Pd(0)/Ag(I) Heck-1,3-dipolar cycloaddition cascade reactions accessing spiro-oxindoles. Concomitant in situ generation of azomethine ylides and dipolarophile. TETRAHEDRON, 2018, 74, 3564-3577.
http://dx.doi.org/10.1016/j.tet.2018.05.017
13. Nural, Y.; Gemili, M.; Seferoglu, N.; Sahin, E.; Ulger, M.; Sari, H. Synthesis, crystal structure, DFT studies, acid dissociation constant, and antimicrobial activity of methyl 2-(4-chlorophenyl)-7a-((4-chlorophenyl)carbamothioyl)-1-oxo-5,5-diphenyl-3-thioxo-hexahydro-1H-pyrrolo[1,2-e]imidazole-6-carboxylate. JOURNAL OF MOLECULAR STRUCTURE, 2018, 1160, 375-382.
http://dx.doi.org/10.1016/j.molstruc.2018.01.099
12. Yaman, S.; çömelekoğlu, .; Değirmenci, E.; Karagül, M.; Yalın, S.; Ballı, E.; Yıldırımcan, S.; Yıldırım, M.; Doğaner, A. . DRUG AND CHEMICAL TOXICOLOGY, 2018, 41, 465-475.
10.1080/01480545.2017.1384005
11. Nural, Y.; Gemili, M.; Yabalak, E.; Coen, L.; Ulger, M. Green synthesis of highly functionalized octahydropyrrolo[3,4-c]pyrrole derivatives using subcritical water, and their anti(myco)bacterial and antifungal activity. ARKIVOC, 2018, 2018, 51-64.
http://dx.doi.org/10.24820/ark.5550190.p010.573
Alıntılanma Sayısı: 1
10. Binzet, G.; Gumus, I.; Dogen, A.; Flörke, U.; Kulcu, N.; Arslan, H. Nickel(II) and copper(II) complexes of N,N -dialkyl- N ′-3-chlorobenzoylthiourea: Synthesis, characterization, crystal structures, Hirshfeld surfaces and antimicrobial activity. ELSEVIER BV, 2018, 1161, 519-529.
http://dx.doi.org/10.1016/j.molstruc.2018.02.073
9. Gülmez, D.; Doğan, .; Boral, B.; Döğen, A.; Ilkit, M.; De hoog, G.; Arikan-akdagli, S. In vitro activities of antifungal drugs against environmental Exophiala isolates and review of the literature. WILEY, 2018, 61, 561-569.
http://dx.doi.org/10.1111/myc.12779
8. Eker, E.; Arslan, B.; Yildirim, M.; Akar, A.; Aras, N. The effect of exposure to 1800 MHz radiofrequency radiation on epidermal growth factor, caspase-3, Hsp27 and p38MAPK gene expressions in the rat eye. BRATISLAVA MEDICAL JOURNAL, 2018, 119, 588-592.
http://dx.doi.org/10.4149/BLL_2018_106
7. Dondas, H.; Belveren, S.; Poyraz, S.; Grigg, R.; Kilner, C.; Ferrándiz-saperas, M.; Selva, E.; Sansano, J. Design and synthesis of novel 1,4-benzodiazepine surrogates as potential CCKA and CCKB antagonists via palladium-catalyzed three-component cascade reactions. TETRAHEDRON, 2018, 74, 6-11.
http://dx.doi.org/10.1016/j.tet.2017.11.017
6. çömelekoğlu, .; Aktaş, S.; Demirbağ, B.; Karagül, M.; Yalın, S.; Yıldırım, M.; Akar, A.; Korunur engiz, B.; Söğüt, F. . BIOELECTROMAGNETICS, 2018, 39, 631-643.
10.1002/bem.22149
5. Hilmioğlu-polat, S.; Sharifynia, S.; öz, Y.; Aslan, M.; Gündoğdu, N.; Serin, A.; Rafati, H.; Mohammadi, F.; Yeşim-metin, D. Genetic Diversity and Antifungal Susceptibility of Candida parapsilosis Sensu Stricto Isolated from Bloodstream Infections in Turkish Patients. SPRINGER NATURE, 2018, 183, 701-708.
http://dx.doi.org/10.1007/s11046-018-0261-x
4. Gemili, M.; Nural, Y.; Keleş, E.; Aydıner, B.; Seferoğlu, N.; Sahin, E.; Sarı, H.; Seferoğlu, Z. Novel 1,4-naphthoquinone N -aroylthioureas: Syntheses, crystal structure, anion recognition properties, DFT studies and determination of acid dissociation constants. JOURNAL OF MOLECULAR LIQUIDS, 2018, 269, 920-932.
http://dx.doi.org/10.1016/j.molliq.2018.08.054
3. Akçay, S.; ülger, M.; Kaynak onurdağ, F.; Dündar, Y. . ACTA CHIMICA SLOVENICA, 2018, 65, 932-938.
10.17344/acsi.2018.4590
2. Nural, Y.; Gemili, M.; Ulger, M.; Sari, H.; De coen, L.; Sahin, E. Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28, 942-946.
https://dx.doi.org/10.1016/j.bmcl.2018.01.045
Alıntılanma Sayısı: 3
1. Belveren, S.; Larrañaga, O.; Poyraz, S.; Döndaş, H.; ülger, M.; şahin, E.; Ferrándiz-saperas, M.; Sansano, J.; Gracia retamosa, D. . SYNTHESIS, 2018, , -.
10.1055/s-0037-1611356